Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | FEN1 | P39748 | 4/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008930 | 0.73 | — | — | |
| SCHEMBL9009539 | 0.70 | JAK2 (0.34) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL9009527 | 0.70 | JAK2 (0.32) | JAK2JAK1JAK3 | |
| SCHEMBL11481064 | 0.69 | BCHE (0.35) | HTR2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL1126594 | 0.67 | GABRA1 (0.32) | ADRA1A | |
| SCHEMBL8139573 | 0.62 | CCNE1 (0.39) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL3959146 | 0.62 | LMNA (0.41) | — | |
| SCHEMBL16655119 | 0.62 | HTR2C (0.36) | ALOX5APFEN1JAK2JAK1TYK2 | |
| SCHEMBL7400755 | 0.61 | CNR2 (0.44) | — | |
| SCHEMBL1126656 | 0.60 | KMT2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |