Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534264 | 0.67 | GABRA1 (0.40) | GABRA1GABRB2 | |
| SCHEMBL1126653 | 0.67 | ALOX5AP (0.36) | ADRA1A | |
| SCHEMBL8603942 | 0.66 | NR3C1 (0.44) | NR3C1ADRB2ADRB1CYP2D6ADRA1A | |
| SCHEMBL31369337 | 0.66 | GABRA1 (0.39) | GABRA1GABRB2ADRB1 | |
| SCHEMBL12701600 | 0.66 | GABRA1 (0.39) | GABRA1GABRB2 | |
| SCHEMBL1126685 | 0.65 | ALDH1A1 (0.46) | PDE4D | |
| SCHEMBL3959146 | 0.64 | LMNA (0.41) | — | |
| SCHEMBL6139412 | 0.63 | ADRA1A (0.32) | ADRA1A | |
| SCHEMBL8207936 | 0.63 | ADRA1A (0.32) | ADRA1A | |
| SCHEMBL10960074 | 0.63 | GABRA1 (0.36) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |