Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264480 | 0.79 | KMT2A (0.60) | KMT2AMAPTALDH1A1CYP3A4GPR139 | |
| SCHEMBL27339510 | 0.74 | KCNK3 (0.46) | KMT2AMAPTALDH1A1TRPA1CYP3A4 | |
| SCHEMBL11260263 | 0.74 | SMN1; SMN2 (0.44) | KMT2AMAPTALDH1A1PTPN1TSHR | |
| SCHEMBL11267948 | 0.74 | MAPT (0.51) | KMT2AMAPTALDH1A1GPR139PTPN1 | |
| SCHEMBL10633432 | 0.69 | TRPA1 (0.46) | KMT2AMAPTTRPA1CYP3A4GPR139 | |
| SCHEMBL11273012 | 0.68 | MAPT (0.47) | KMT2AMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL11267199 | 0.68 | SMN1; SMN2 (0.44) | KMT2AMAPTALDH1A1PTPN1KDM4E | |
| SCHEMBL277930 | 0.67 | — | — | |
| SCHEMBL11261713 | 0.67 | CRBN (0.36) | KMT2AMAPTALDH1A1TSHRUSP2 | |
| SCHEMBL10811976 | 0.67 | TRPA1 (0.56) | KMT2AMAPTALDH1A1TRPA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |