Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267137 | 0.79 | RAB9A (0.48) | SMN1; SMN2GAATP53RAB9AALDH1A1 | |
| SCHEMBL11269537 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2GAARAB9AALDH1A1POLB | |
| SCHEMBL9972664 | 0.75 | CES2 (0.52) | SMN1; SMN2GAATP53RAB9AALDH1A1 | |
| SCHEMBL11264480 | 0.74 | KMT2A (0.60) | SMN1; SMN2GAAALDH1A1POLBHPGD | |
| SCHEMBL11266779 | 0.74 | KMT2A (0.40) | ALDH1A1HPGDMAPTL3MBTL1PTPN1 | |
| SCHEMBL27339507 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2GAATP53RAB9AALDH1A1 | |
| SCHEMBL8829982 | 0.73 | ALDH1A1 (0.63) | SMN1; SMN2RAB9AALDH1A1POLBHPGD | |
| SCHEMBL16118675 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2GAATP53RAB9AALDH1A1 | |
| SCHEMBL11259579 | 0.72 | PAM (0.62) | GAAALDH1A1HPGDTDP1L3MBTL1 | |
| SCHEMBL16072791 | 0.71 | CES2 (0.47) | SMN1; SMN2GAATP53RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0001989-A1 | Substituted mercapto acid amides, process for their preparation, pharmaceutical composition containing same and their use | MERCK & CO. INC. (US) | 1979-05-30 | — | — | EP | disclosed |