Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264480 | 0.91 | KMT2A (0.60) | MAPTALDH1A1KMT2AGPR139SMN1; SMN2 | |
| SCHEMBL11266779 | 0.74 | KMT2A (0.40) | MAPTALDH1A1KMT2AGPR139L3MBTL1 | |
| SCHEMBL12642206 | 0.74 | GPR139 (0.62) | MAPTALDH1A1KMT2AGPR139SMN1; SMN2 | |
| SCHEMBL11267199 | 0.73 | SMN1; SMN2 (0.44) | MAPTALDH1A1KMT2ASMN1; SMN2PTPN1 | |
| SCHEMBL9371115 | 0.72 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2AGPR139SMN1; SMN2 | |
| SCHEMBL17702607 | 0.72 | SMN1; SMN2 (0.56) | MAPTALDH1A1SMN1; SMN2L3MBTL1PTPN1 | |
| SCHEMBL11259579 | 0.72 | PAM (0.62) | ALDH1A1KMT2AL3MBTL1KDM4EHPGD | |
| Biphenyl SCHEMBL28188851 | 0.72 | SMN1; SMN2 (0.56) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11261370 | 0.71 | MTNR1A (0.41) | MAPTALDH1A1KMT2AGPR139L3MBTL1 | |
| SCHEMBL11266780 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |