SCHEMBL1126695

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30234686	0.92	MAPT (0.37)	NPY2RMAPTTP53LMNATHRB
	SCHEMBL1126444	0.92	NPC1 (0.41)	NPY2RMAPTTP53LMNAHTT
	SCHEMBL1127148	0.92	MAPT (0.37)	NPY2RMAPTTP53LMNATHRB
	SCHEMBL23488118	0.90	MAPT (0.35)	NPY2RMAPTTP53LMNATHRB
	SCHEMBL30234731	0.89	MAPT (0.42)	MAPTTP53LMNAHTTALDH1A1
	SCHEMBL1127284	0.89	MAPT (0.42)	MAPTTP53LMNAHTTALDH1A1
	SCHEMBL1645685	0.87	MAPT (0.53)	NPY2RMAPTTP53LMNATHRB
	SCHEMBL1989247	0.86	MAPT (0.40)	MAPTTP53LMNAALDH1A1MEN1
	SCHEMBL942509	0.85	NPY2R (0.38)	NPY2RMAPTTP53LMNATHRB
	SCHEMBL1647462	0.85	MAPT (0.51)	NPY2RMAPTLMNATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.