SCHEMBL1126444

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126695	0.92	NPY2R (0.41)	RAB9ANPY2RHTTTP53MAPT
	SCHEMBL30234686	0.92	MAPT (0.37)	RAB9ANPY2RHTTTP53MAPT
	SCHEMBL1127148	0.92	MAPT (0.37)	RAB9ANPY2RHTTTP53MAPT
	SCHEMBL23488118	0.89	MAPT (0.35)	RAB9ANPY2RHTTTP53MAPT
	SCHEMBL1127012	0.88	NPC1 (0.40)	NPC1RAB9ACHRM1NPY2RHTT
	SCHEMBL1991280	0.88	MAPT (0.42)	NPC1RAB9ACHRM1MALT1HTT
	SCHEMBL30234731	0.88	MAPT (0.42)	NPC1RAB9AHTTTP53MAPT
	SCHEMBL1127284	0.88	MAPT (0.42)	NPC1RAB9AHTTTP53MAPT
	SCHEMBL1990112	0.86	CHRM1 (0.38)	NPC1RAB9ACHRM1MALT1NPY2R
	SCHEMBL943289	0.86	NPY2R (0.37)	NPC1RAB9ACHRM1NPY2RHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.