Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126683 | 0.73 | KDM4E (0.40) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL20120137 | 0.72 | CYP2A6 (0.40) | CYP2A6CYP2E1CYP2B6FYNIMPDH2 | |
| SCHEMBL1127129 | 0.71 | NUDT1 (0.42) | MEN1KMT2AHPGDSLC6A9MAOB | |
| SCHEMBL1126656 | 0.68 | KMT2A (0.39) | KMT2ACYP2A6MAPTALDH1A1KDM4E | |
| SCHEMBL6057266 | 0.65 | — | — | |
| SCHEMBL22744325 | 0.65 | CYP17A1 (0.47) | CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL7459145 | 0.63 | CYP2A6 (0.35) | MEN1KMT2AGFERCYP2A6FYN | |
| SCHEMBL7462797 | 0.63 | MEN1 (0.35) | MEN1KMT2AGFERCYP2A6FYN | |
| SCHEMBL19824760 | 0.63 | TAAR1 (0.50) | MEN1KMT2AHSD17B10MAPTALDH1A1 | |
| SCHEMBL2898794 | 0.62 | ADRB2 (0.49) | MEN1KMT2AFYNALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |