Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | STK4 | Q13043 | 1/20 | 0.34 |
| ▸ | STK3 | Q13188 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126656 | 0.75 | KMT2A (0.39) | GAAKMT2AMAOBHPGD | |
| SCHEMBL2285042 | 0.72 | IDO1 (0.54) | NUDT1TP53MEN1GAAKMT2A | |
| SCHEMBL1126701 | 0.71 | MEN1 (0.36) | MEN1KMT2ASLC6A9MAOBHPGD | |
| SCHEMBL1126618 | 0.69 | EGFR (0.40) | NUDT1TP53EGFRSLC6A9HPGD | |
| SCHEMBL24612554 | 0.69 | MAOB (0.48) | TP53MAOBTAAR1 | |
| SCHEMBL21507854 | 0.68 | KMT2A (0.48) | MEN1KMT2A | |
| SCHEMBL1126683 | 0.68 | KDM4E (0.40) | TP53MEN1GAAKMT2AHPGD | |
| SCHEMBL3096336 | 0.68 | TAAR1 (0.57) | IDO1TAAR1 | |
| SCHEMBL2220568 | 0.67 | PDE4B (0.42) | TP53IDO1MAOBNOTUMNR1I3 | |
| SCHEMBL26173372 | 0.66 | MAPT (0.44) | EGFRGAANOTUMHPGDSTK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |