Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126701 | 0.73 | MEN1 (0.36) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1126656 | 0.71 | KMT2A (0.39) | KDM4EALDH1A1DPP4GAAMAPT | |
| SCHEMBL4653136 | 0.69 | TDO2 (0.43) | KDM4EALDH1A1DPP4GAAMAPT | |
| SCHEMBL1127129 | 0.68 | NUDT1 (0.42) | GAAHPGDMEN1KMT2ATP53 | |
| SCHEMBL7812159 | 0.67 | KCNH2 (0.40) | KDM4EALDH1A1DPP4GAAMAPT | |
| SCHEMBL2094586 | 0.66 | LTA4H (0.44) | KDM4EALDH1A1DPP4GAAMAPT | |
| SCHEMBL5747483 | 0.65 | — | — | |
| SCHEMBL19953474 | 0.64 | SLC6A9 (0.41) | KDM4EDPP4GAAHPGDLTA4H | |
| SCHEMBL28079025 | 0.62 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL10385976 | 0.62 | LTA4H (0.60) | KDM4EALDH1A1DPP4GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |