Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 11/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191876 | 0.82 | ACE (0.39) | FFAR2ACEHTTPOLBGAA | |
| SCHEMBL10969787 | 0.82 | ACE (0.57) | FFAR2ACEHTTPOLB | |
| SCHEMBL11195295 | 0.81 | ACE (0.38) | FFAR2ACEHTTPOLB | |
| SCHEMBL11191943 | 0.78 | ALDH1A1 (0.43) | FFAR2ACEHTTPOLB | |
| SCHEMBL11192578 | 0.78 | LMNA (0.53) | FFAR2ACEHTTPOLB | |
| SCHEMBL11267042 | 0.78 | ACE (0.53) | FFAR2ACEHTTPOLBGAA | |
| SCHEMBL11183354 | 0.78 | GAA (0.59) | FFAR2HTTPOLBGAARAB9A | |
| SCHEMBL11257867 | 0.77 | HSD17B10 (0.45) | FFAR2ACEPOLBGAARAB9A | |
| SCHEMBL11102513 | 0.76 | ACE (0.68) | FFAR2ACEHTTPOLBGAA | |
| SCHEMBL11189466 | 0.75 | GAA (0.37) | FFAR2POLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | claimed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |