Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 9/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11192578 | 0.87 | LMNA (0.53) | ACEALDH1A1POLBHPGDLMNA | |
| SCHEMBL11191943 | 0.87 | ALDH1A1 (0.43) | ACEALDH1A1POLBHPGDLMNA | |
| SCHEMBL11257867 | 0.85 | HSD17B10 (0.45) | ACEALDH1A1POLBHPGDLMNA | |
| SCHEMBL11191876 | 0.82 | ACE (0.39) | ACEALDH1A1POLBHPGDLMNA | |
| SCHEMBL11267053 | 0.82 | FFAR2 (0.41) | ACEPOLBFFAR2HTT | |
| SCHEMBL11385089 | 0.81 | ACE (0.54) | ACEALDH1A1POLBHPGDLMNA | |
| SCHEMBL11195295 | 0.81 | ACE (0.38) | ACEALDH1A1POLBHPGDLMNA | |
| SCHEMBL11186352 | 0.81 | POLB (0.40) | ACEALDH1A1POLBHPGDLMNA | |
| SCHEMBL11190307 | 0.80 | ACE (0.38) | ACEALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL10970167 | 0.80 | MAPT (0.43) | ACEALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482709-A | Inclusion compounds of cyclodextrin with sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | claimed |
| EP-0072868-A1 | CYCLODEXTRIN CLATHRATE COMPOUNDS OF SULFUR-CONTAINING COMPOUNDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-03-02 | — | — | EP | claimed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | claimed |
| EP-0048763-B1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0072868-B1 | CYCLODEXTRIN CLATHRATE COMPOUNDS OF SULFUR-CONTAINING COMPOUNDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| US-4482709-A | Inclusion compounds of cyclodextrin with sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4410542-A | HYPOTENSIVE AGENTS, PYRROLINE-1,2-DICARBOXYLIC ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |