Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548441 | 0.85 | TDP1 (0.58) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL30726456 | 0.85 | TDP1 (0.58) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL27039902 | 0.82 | ALDH1A1 (0.55) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL10385970 | 0.81 | MAPT (0.59) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL29674877 | 0.80 | HTT (0.66) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL3911774 | 0.80 | HTT (0.66) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL5625355 | 0.80 | FFAR4 (0.65) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL10534498 | 0.79 | HTT (0.71) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11835914 | 0.79 | ALDH1A1 (0.59) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL27685352 | 0.79 | MAPT (0.55) | TSHRTDP1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437123-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | claimed |
| EP-0999823-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2011-10-05 | — | — | EP | claimed |
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | AVOCA LLC | 2011-01-27 | — | — | US | claimed |
| US-7799092-B2 | Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer | L'OREAL S.A. (FR) | 2010-09-21 | — | — | US | claimed |
| US-7736395-B2 | direct dyes | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1437123-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2007-06-06 | — | — | EP | claimed |
| US-20070033743-A1 | direct dyes | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| EP-0673926-A1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | L'OREAL (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0646108-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| EP-0646109-A1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES. | OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| EP-0480829-B1 | Hair dyeing composition containing anthraquinones | OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| WO-1994000415-A1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| US-5226924-A | 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM | L'OREAL (FR) | 1993-07-13 | — | — | US | claimed |
| EP-0480829-A1 | Hair dyeing composition containing anthraquinones | L'OREAL (FR) | 1992-04-15 | — | — | EP | claimed |
| US-4935032-A | DIRECT NITROBENZENE DYE | L'OREAL (FR) | 1990-06-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | KRT18, BRD7, KAT7 | TSHR 3126/4885TDP1 2418/4885ALDH1A1 930/4885 |
| US-20070033743-A1 | direct dyes | KRT18, DSG1, DSP | TSHR 4673/4885TDP1 1167/4885ALDH1A1 385/4885 |
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | UFM1, UHRF1, CUTA | TSHR 2543/4885TDP1 2312/4885ALDH1A1 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.