Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 6/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL10625309 | 0.87 | RAB9A (0.44) | PARP1SMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL36282 | 0.87 | RAB9A (0.44) | PARP1SMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL2496637 | 0.84 | RAB9A (0.49) | PARP1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL11274010 | 0.83 | ALDH1A1 (0.45) | PARP1SMN1; SMN2KDM4EALDH1A1ELANE | |
| Benzimidazole SCHEMBL11267172 | 0.80 | RAB9A (0.46) | PARP1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL11271306 | 0.78 | CYP1A2 (0.52) | PARP1KDM4EALDH1A1HPGDCA12 | |
| Benzimidazole SCHEMBL28119750 | 0.77 | RAB9A (0.48) | PARP1SMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL30988876 | 0.76 | KMT2A (0.44) | PARP1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL718185 | 0.76 | CYP1A2 (0.54) | PARP1KDM4EALDH1A1HPGDCA12 | |
| SCHEMBL29415469 | 0.76 | CYP1A2 (0.54) | PARP1KDM4EALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336383-A | 1-1-Binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid compounds, method of preparation and use thereof for the synthesis of asymmetric derivatives of 3,4,9,10-perylenetetracarboxylic acid, and for dyeing and printing of textile materials | VOROZHTSOV GEORGY N | 1982-06-22 | — | — | US | disclosed |
| US-4336383-A | 1-1-Binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid compounds, method of preparation and use thereof for the synthesis of asymmetric derivatives of 3,4,9,10-perylenetetracarboxylic acid, and for dyeing and printing of textile materials | VOROZHTSOV GEORGY N | 1982-06-22 | — | — | US | disclosed |