Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | C1R | P00736 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL11267445 | 0.83 | PARP1 (0.40) | ALDH1A1PARP1C1RKDM4EGPR35 | |
| SCHEMBL11271306 | 0.74 | CYP1A2 (0.52) | ALDH1A1PARP1CYP1A2KDM4ECYP2C9 | |
| SCHEMBL29415469 | 0.72 | CYP1A2 (0.54) | ALDH1A1PARP1CYP1A2KDM4ECYP2C9 | |
| SCHEMBL718185 | 0.72 | CYP1A2 (0.54) | ALDH1A1PARP1CYP1A2KDM4ECYP2C9 | |
| SCHEMBL29908920 | 0.72 | ALDH1A1 (0.56) | ALDH1A1F7F3PARP1APEX1 | |
| SCHEMBL1445052 | 0.72 | ALDH1A1 (0.56) | ALDH1A1F7F3PARP1APEX1 | |
| SCHEMBL11404855 | 0.71 | ALDH1A1 (0.55) | ALDH1A1F7F3PARP1APEX1 | |
| Benzimidazole SCHEMBL10625309 | 0.70 | RAB9A (0.44) | ALDH1A1PARP1CYP1A2KDM4EMEN1 | |
| Benzimidazole SCHEMBL36282 | 0.70 | RAB9A (0.44) | ALDH1A1PARP1CYP1A2KDM4EMEN1 | |
| SCHEMBL8817622 | 0.67 | PRKCI (0.52) | ALDH1A1PARP1APEX1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336383-A | 1-1-Binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid compounds, method of preparation and use thereof for the synthesis of asymmetric derivatives of 3,4,9,10-perylenetetracarboxylic acid, and for dyeing and printing of textile materials | VOROZHTSOV GEORGY N | 1982-06-22 | — | — | US | disclosed |