SCHEMBL11271306

SCHEMBL11271306

O=C(O)c1ccc(C(=O)O)c2c3ccc(c(=O)oc(=O)c4ccc3c3c(C(=O)O)ccc(C(=O)O)c43)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
GPR35 Q9HC97 8/20 0.42
TYMS P04818 1/20 0.41
PARP1 P09874 1/20 0.39
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA4 P22748 3/20 0.38
CA5A P35218 3/20 0.38
CA7 P43166 3/20 0.38
CA9 Q16790 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA5B Q9Y2D0 3/20 0.38
CA3 P07451 2/20 0.38
CA6 P23280 2/20 0.38
MAOB P27338 2/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 2/20 0.38
GLA P06280 2/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718185 0.98 CYP1A2 (0.54) CYP1A2GPR35TYMSPARP1CA12
SCHEMBL29415469 0.98 CYP1A2 (0.54) CYP1A2GPR35TYMSPARP1CA12
SCHEMBL2804188 0.85 ALDH1A1 (0.51) CYP1A2GPR35TYMSPARP1CA12
SCHEMBL9521993 0.83 GPR35 (0.47) CYP1A2GPR35TYMSPARP1ALDH1A1
SCHEMBL14674737 0.80 GPR35 (0.47) CYP1A2GPR35CA12CA1CA4
SCHEMBL761372 0.78 PARP1 (0.53) CYP1A2GPR35TYMSPARP1CA12
Benzimidazole SCHEMBL11267445 0.78 PARP1 (0.40) GPR35PARP1CA12CA9ALDH1A1
SCHEMBL30141 0.77 CYP1A2 (0.78) CYP1A2TYMSPARP1CA12CA1
SCHEMBL30117300 0.77 CYP1A2 (0.78) CYP1A2TYMSPARP1CA12CA1
SCHEMBL3668375 0.76 GPR35 (0.51) GPR35TYMSPARP1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4336383-A 1-1-Binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid compounds, method of preparation and use thereof for the synthesis of asymmetric derivatives of 3,4,9,10-perylenetetracarboxylic acid, and for dyeing and printing of textile materials VOROZHTSOV GEORGY N 1982-06-22 US disclosed
US-4336383-A 1-1-Binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid compounds, method of preparation and use thereof for the synthesis of asymmetric derivatives of 3,4,9,10-perylenetetracarboxylic acid, and for dyeing and printing of textile materials VOROZHTSOV GEORGY N 1982-06-22 US disclosed
US-3960867-A Method of producing perylenetetracarboxylic acid derivatives DOKUNIKHIN NIKOLAI STEPANOVICH 1976-06-01 US disclosed
US-3959285-A Imides of 1,1'-dinaphthyl-4,4',5,5',8,8'-hexacarboxylic acid DOKUNIKHIN NIKOLAI STEPANOVICH 1976-05-25 US disclosed