Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874965 | 0.87 | KMT2A (0.47) | RAD51ALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL11268915 | 0.82 | ALDH1A1 (0.54) | RAD51ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL11276928 | 0.80 | KMT2A (0.50) | RAD51ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL11270774 | 0.80 | AR (0.51) | NOTUMGAA | |
| SCHEMBL11271240 | 0.79 | KDM4E (0.30) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11270496 | 0.79 | ELANE (0.44) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL11280801 | 0.78 | ALDH1A1 (0.48) | RAD51ALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL11267668 | 0.78 | KMT2A (0.49) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL11278830 | 0.77 | TSHR (0.43) | ALDH1A1SMN1; SMN2BCL2A1KDM4E | |
| SCHEMBL11271202 | 0.75 | HTR7 (0.45) | ALDH1A1HPGDSMN1; SMN2L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042570-A1 | 20-Deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-12-30 | — | — | EP | claimed |
| US-4262118-A | 2-Decarboxy-2-tetrazolyl-19-hydroxy-19-methyl-PG compounds | THE UPJOHN COMPANY (US) | 1981-04-14 | — | — | US | claimed |
| EP-0024570-B1 | 5-IMINO-IMIDAZOLINE-2-ONES, HERBICIDES CONTAINING THEM AND PROCESS FOR DESTRUCTING UNDESIRED PLANTS | BASF Aktiengesellschaft (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0042570-A1 | 20-Deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4262118-A | 2-Decarboxy-2-tetrazolyl-19-hydroxy-19-methyl-PG compounds | THE UPJOHN COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| EP-0024570-A1 | 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants | BASF Aktiengesellschaft (DE) | 1981-03-11 | — | — | EP | disclosed |