Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271202 | 0.86 | HTR7 (0.45) | ALDH1A1SMN1; SMN2RAB9AMAPTCYP3A4 | |
| SCHEMBL10874965 | 0.84 | KMT2A (0.47) | ALDH1A1SMN1; SMN2MAPTRAD51HPGD | |
| SCHEMBL11268915 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTHSD17B10RAD51 | |
| SCHEMBL11278091 | 0.82 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL11276928 | 0.81 | KMT2A (0.50) | ALDH1A1SMN1; SMN2MAPTRAD51HPGD | |
| SCHEMBL11267472 | 0.78 | RAD51 (0.42) | ALDH1A1SMN1; SMN2MAPTRAD51HPGD | |
| SCHEMBL11271240 | 0.76 | KDM4E (0.30) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11270496 | 0.76 | ELANE (0.44) | ALDH1A1SMN1; SMN2MAPTHSD17B10CYP1A2 | |
| SCHEMBL11267668 | 0.76 | KMT2A (0.49) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11270774 | 0.75 | AR (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024570-B1 | 5-IMINO-IMIDAZOLINE-2-ONES, HERBICIDES CONTAINING THEM AND PROCESS FOR DESTRUCTING UNDESIRED PLANTS | BASF Aktiengesellschaft (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0024570-A1 | 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants | BASF Aktiengesellschaft (DE) | 1981-03-11 | — | — | EP | disclosed |