Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269396 | 0.82 | LMNA (0.57) | ALDH1A1LMNAHTTHSD17B10USP2 | |
| SCHEMBL8351644 | 0.82 | ALDH1A1 (0.59) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL13485769 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL13113137 | 0.80 | PKM (0.51) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL15563329 | 0.79 | ALDH1A1 (0.57) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL8429706 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL25740966 | 0.75 | LMNA (0.54) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL11627434 | 0.75 | ALDH1A1 (0.56) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL147071 | 0.74 | FFAR1 (0.65) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL11442961 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAPKMHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |