Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267482 | 0.82 | ALDH1A1 (0.56) | LMNAHTTHSD17B10ALDH1A1USP2 | |
| SCHEMBL11468216 | 0.81 | FFAR1 (0.61) | LMNAKMT2AMEN1FFAR1HTT | |
| SCHEMBL13799728 | 0.81 | FFAR1 (0.52) | LMNAKMT2AMEN1FFAR1HTT | |
| SCHEMBL13485781 | 0.79 | ANPEP (0.66) | LMNAKMT2AMEN1FFAR1HTT | |
| SCHEMBL7407 | 0.78 | FFAR1 (0.68) | LMNAKMT2AMEN1FFAR1MTNR1A | |
| SCHEMBL8008062 | 0.77 | FFAR1 (0.61) | LMNAKMT2AMEN1FFAR1HTT | |
| SCHEMBL2210143 | 0.77 | FFAR1 (0.61) | LMNAKMT2AMEN1FFAR1MTNR1A | |
| SCHEMBL10717383 | 0.77 | CYP1A2 (0.68) | LMNAKMT2AMEN1FFAR1HTT | |
| SCHEMBL13527504 | 0.76 | RAB9A (0.57) | LMNAKMT2AMEN1FFAR1HTT | |
| SCHEMBL6796256 | 0.76 | ALDH1A1 (0.78) | LMNAKMT2AMEN1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |