Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255922 | 0.91 | ALDH1A1 (0.37) | PPARGADAM17MMP1HRH3ADAMTS4 | |
| SCHEMBL11252783 | 0.81 | PTGS2 (0.39) | HRH3 | |
| SCHEMBL11267562 | 0.72 | NISCH (0.49) | HTR2CGAAFFAR1P2RY2GPR17 | |
| Pyrrole SCHEMBL6782101 | 0.67 | HTR2C (0.51) | HTR2CPPARG | |
| SCHEMBL11263728 | 0.64 | ALDH1A1 (0.37) | GAA | |
| SCHEMBL1234573 | 0.64 | NR1H4 (0.50) | HTR2CPPARGFFAR1 | |
| SCHEMBL1487652 | 0.63 | TSHR (0.52) | — | |
| SCHEMBL27602928 | 0.62 | BCHE (0.47) | GAAP2RY2GPR17ADAMTS4CKS1B | |
| Hydrochloric Acid SCHEMBL28265694 | 0.61 | TSHR (0.50) | — | |
| SCHEMBL11264214 | 0.61 | NISCH (0.68) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343808-A | Method of inhibiting sickling of sickle erythrocytes | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |