Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267568 | 0.91 | HTR2C (0.39) | ADAM17MMP1HRH3ADAMTS4MMP13 | |
| SCHEMBL11252783 | 0.84 | PTGS2 (0.39) | ALDH1A1HRH3MAPT | |
| SCHEMBL11162001 | 0.71 | POLB (0.41) | ALDH1A1MAPT | |
| SCHEMBL11255915 | 0.69 | NISCH (0.48) | ALDH1A1PRSS1ACRMAPT | |
| SCHEMBL1619491 | 0.69 | MAPT (0.47) | ALDH1A1HRH2HRH1HRH3PRSS1 | |
| SCHEMBL11232306 | 0.68 | KMT2A (0.40) | ALDH1A1MAPT | |
| SCHEMBL11233336 | 0.67 | MAPT (0.41) | ALDH1A1MAPT | |
| SCHEMBL11263728 | 0.67 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL5540095 | 0.65 | MMP2 (0.48) | ALDH1A1HRH2HRH1PRSS1ACR | |
| SCHEMBL1619492 | 0.65 | ALDH1A1 (0.41) | ALDH1A1RXFP1HRH3PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343808-A | Method of inhibiting sickling of sickle erythrocytes | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |