Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283712 | 0.84 | TOP2A (0.37) | LMNATP53THRBTOP2ATOP2B | |
| SCHEMBL11266028 | 0.82 | PLA2G10 (0.35) | LMNATOP2ATOP2BL3MBTL1TDP1 | |
| SCHEMBL11281949 | 0.79 | PTGS1 (0.31) | LMNAFFAR1HTTTDP1PTGS1 | |
| SCHEMBL11269114 | 0.78 | PLA2G10 (0.44) | LMNATP53TOP2ATOP2BHTT | |
| SCHEMBL11277217 | 0.75 | TOP2A (0.36) | LMNATP53THRBTOP2ATOP2B | |
| SCHEMBL11266232 | 0.73 | CARM1 (0.36) | L3MBTL1TDP1ATMPTGS1KMT2A | |
| SCHEMBL11280499 | 0.71 | ALDH1A1 (0.31) | TDP1ALDH1A1KDM4E | |
| SCHEMBL11276790 | 0.71 | ALDH1A1 (0.38) | TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11283401 | 0.71 | LMNA (0.35) | LMNATP53FFAR1TOP2ATOP2B | |
| SCHEMBL11284589 | 0.71 | P2RX3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338326-A | PESTICIDES | UNION CARBIDE CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |