Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283712 | 0.91 | TOP2A (0.37) | TOP2ATOP2BSCN9AHTR3EHTR3B | |
| SCHEMBL11279541 | 0.80 | P2RX3 (0.34) | LMNAKDM4EGPBAR1CYSLTR1TP53 | |
| SCHEMBL11268087 | 0.75 | LMNA (0.35) | TOP2ATOP2BLMNAKDM4ECYSLTR1 | |
| SCHEMBL11264170 | 0.75 | CARM1 (0.34) | KDM4ETSHRGAA | |
| SCHEMBL11269114 | 0.74 | PLA2G10 (0.44) | TOP2ATOP2BSCN9ALMNAKDM4E | |
| SCHEMBL11282335 | 0.73 | P2RX3 (0.41) | — | |
| SCHEMBL11275943 | 0.72 | P2RX3 (0.34) | TSHRGAA | |
| SCHEMBL11271875 | 0.72 | SCN9A (0.37) | SCN9A | |
| SCHEMBL11275322 | 0.71 | ALDH1A1 (0.36) | TOP2ATOP2BLMNAKDM4E | |
| SCHEMBL11272118 | 0.71 | TOP2A (0.32) | TOP2ATOP2BLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338326-A | PESTICIDES | UNION CARBIDE CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |