Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255607 | 0.90 | MAPT (0.56) | HTTSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL11261631 | 0.87 | GAA (0.51) | HTTSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL11048349 | 0.79 | GAA (0.51) | GAAALDH1A1 | |
| SCHEMBL13040955 | 0.72 | ALDH1A1 (0.68) | HTTSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL9327915 | 0.70 | SMN1; SMN2 (0.76) | HTTSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL11043941 | 0.69 | ALDH1A1 (0.36) | SMN1; SMN2GAAALDH1A1MAPTKDM4E | |
| SCHEMBL18911360 | 0.69 | HTT (0.44) | HTTSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL7498372 | 0.68 | HTT (0.81) | HTTSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL11425713 | 0.67 | GPBAR1 (0.50) | SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL10770483 | 0.66 | POLB (0.51) | HTTGAAALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353734-A | PRE- AND POSTEMERGENCE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-10-12 | — | — | US | claimed |