SCHEMBL7498372

SCHEMBL7498372

O=C1CC(Nc2ccccc2)C(=O)N1c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.81
ALDH1A1 P00352 12/20 0.74
MAPT P10636 10/20 0.74
GAA P10253 6/20 0.74
GFER P55789 3/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
ALOX12 P18054 1/20 0.71
KDM4E B2RXH2 2/20 0.63
LMNA P02545 1/20 0.63
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
TSHR P16473 1/20 0.55
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9635105 0.81 KDM4E (0.69) HTTALDH1A1MAPTGAAGFER
SCHEMBL13040955 0.78 ALDH1A1 (0.68) HTTALDH1A1MAPTGAASMN1; SMN2
SCHEMBL22446309 0.78 KDM4E (0.64) HTTALDH1A1MAPTGAAGFER
SCHEMBL20029157 0.76 HTT (0.54) HTTALDH1A1MAPTGAAGFER
SCHEMBL16311183 0.75 KDM4E (0.61) HTTALDH1A1MAPTGAAGFER
SCHEMBL13040961 0.74 GAA (0.65) HTTALDH1A1MAPTGAAGFER
SCHEMBL16615639 0.74 MAPT (0.63) HTTALDH1A1MAPTGAAGFER
SCHEMBL14159537 0.74 MAPT (0.84) HTTALDH1A1MAPTGAASMN1; SMN2
SCHEMBL13479538 0.74 ALDH1A1 (1.00) HTTALDH1A1MAPTGAAGFER
SCHEMBL26050589 0.73 HTT (0.54) HTTALDH1A1MAPTGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110198927-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-08-12 CN claimed
EP-3636634-B1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEMICAL LTD (KR) 2022-06-22 EP claimed
US-11345661-B2 Method for purifying N-substituted maleimide LG CHEM, LTD. (KR) 2022-05-31 US claimed
US-20210355083-A1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEM, LTD. (KR) 2021-11-18 US claimed
US-10899708-B2 Method for purifying n-substituted maleimide LG CHEM, LTD. (KR) 2021-01-26 US claimed
US-20200207710-A1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEM, LTD. (KR) 2020-07-02 US claimed
EP-3636634-A1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG Chem, Ltd. (KR) 2020-04-15 EP claimed
CN-110418783-A Process for purifying N-substituted maleimides LG CHEMICAL LTD 2019-11-05 CN claimed
CN-110198927-A Process for purifying N-substituted maleimides 株式会社LG化学 2019-09-03 CN claimed
EP-2690116-B1 N-PHENYLMALEIMIDE COMPOUND AND COPOLYMER COMPOSITION OBTAINED USING SAME NIPPON CATALYTIC CHEM IND (JP) 2019-08-07 EP claimed
US-9631033-B2 N-phenylmaleimide compound and copolymer composition obtained using same NIPPON SHOKUBAI CO., LTD. (JP) 2017-04-25 US claimed
CN-103298845-B N-phenylmaleimide compound and copolymer composition obtained using same 株式会社日本触媒 2016-11-23 CN claimed
EP-2690116-A1 N-PHENYLMALEIMIDE COMPOUND AND COPOLYMER COMPOSITION OBTAINED USING SAME Nippon Shokubai Co., Ltd. (JP) 2014-01-29 EP claimed
US-20140011959-A1 N-PHENYLMALEIMIDE COMPOUND AND COPOLYMER COMPOSITION OBTAINED USING SAME NIPPON SHOKUBAI CO., LTD. (JP) 2014-01-09 US claimed
CN-103298845-A N-phenylmaleimide compound and copolymer composition obtained using same NIPPON CATALYTIC CHEM IND 2013-09-11 CN claimed
JP-1250346-A None JP disclosed
JP-1250347-A None JP disclosed
EP-0334497-A2 Method for production of maleimides NIPPON SHOKUBAI CO., LTD. (JP) 1989-09-27 EP disclosed
US-4757146-A Method for the preparation of quinoline-2,3-dicarboxylic acid AMERICAN CYANAMID COMPANY (US) 1988-07-12 US disclosed
EP-0257433-A2 Method for the preparation of quinoline-2,3-dicarboxylic acid AMERICAN CYANAMID COMPANY (US) 1988-03-02 EP disclosed