Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266142 | 0.86 | ALDH1A1 (0.44) | MAPTHTTALDH1A1HPGDSMN1; SMN2 | |
| Chlozolinate SCHEMBL10347793 | 0.85 | TSHR (0.40) | MAPTALDH1A1OPRM1TSHRAR | |
| Chlozolinate SCHEMBL10638292 | 0.85 | TSHR (0.40) | MAPTALDH1A1OPRM1TSHRAR | |
| Chlozolinate SCHEMBL747833 | 0.82 | AR (0.40) | MAPTALDH1A1TSHRARLMNA | |
| SCHEMBL11277121 | 0.81 | MAPT (0.44) | MAPTALDH1A1OPRM1GAASLC6A4 | |
| SCHEMBL11269869 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL11263372 | 0.81 | ALDH1A1 (0.39) | MAPTMAPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL11269738 | 0.79 | ALDH1A1 (0.35) | MAPTMAPK1ALDH1A1OPRM1TSHR | |
| Chlozolinate SCHEMBL10456638 | 0.78 | TSHR (0.56) | MAPTALDH1A1OPRM1TSHRTP53 | |
| Chlozolinate SCHEMBL27816364 | 0.75 | KDM4E (0.34) | MAPTMAPK1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342773-A | N-Aryl-1,3-oxazolidine-2,4-diones exerting a fungicidal, systemic action in the field | MONTEDISON S.P.A. (IT) | 1982-08-03 | — | — | US | claimed |