SCHEMBL11269738

SCHEMBL11269738

CCOC(=O)C1(C)OC(=O)N(c2cc(F)cc(F)c2)C1=O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
MAPT P10636 2/20 0.35
GLA P06280 1/20 0.35
TRPV1 Q8NER1 1/20 0.34
AR P10275 1/20 0.34
OPRM1 P35372 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
HCAR3 P49019 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
TSHR P16473 1/20 0.31
XPO1 O14980 1/20 0.31
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11269869 0.87 ALDH1A1 (0.41) ALDH1A1MAPTGLACTDSP1TSHR
Chlozolinate SCHEMBL21229 0.86 TSHR (0.40) ALDH1A1MAPTGLAAROPRM1
Chlozolinate SCHEMBL10347793 0.86 TSHR (0.40) ALDH1A1MAPTGLAAROPRM1
Chlozolinate SCHEMBL10638292 0.86 TSHR (0.40) ALDH1A1MAPTGLAAROPRM1
SCHEMBL11263372 0.84 ALDH1A1 (0.39) ALDH1A1MAPTGLACTDSP1MAPK1
Chlozolinate SCHEMBL747833 0.82 AR (0.40) ALDH1A1MAPTGLAARTSHR
SCHEMBL11277121 0.82 MAPT (0.44) ALDH1A1MAPTGLAOPRM1CTDSP1
SCHEMBL11266142 0.79 ALDH1A1 (0.44) ALDH1A1MAPTMEN1KMT2A
SCHEMBL11268442 0.79 MAPT (0.45) ALDH1A1MAPTGLAAROPRM1
Chlozolinate SCHEMBL10456638 0.79 TSHR (0.56) ALDH1A1MAPTGLAOPRM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4342773-A N-Aryl-1,3-oxazolidine-2,4-diones exerting a fungicidal, systemic action in the field MONTEDISON S.P.A. (IT) 1982-08-03 US claimed