Chlozolinate

Chlozolinate

SCHEMBL747833

CC1(C)OC(=O)N(c2cc(Cl)cc(Cl)c2)C1=O.CCOC(=O)C1(C)OC(=O)N(c2cc(Cl)cc(Cl)c2)C1=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.40
TSHR P16473 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 5/20 0.36
TP53 P04637 1/20 0.35
MAPT P10636 3/20 0.34
USP2 O75604 1/20 0.34
GLA P06280 1/20 0.34
OPRK1 P41145 1/20 0.34
RECQL P46063 1/20 0.34
CDC25B P30305 1/20 0.33
LMNA P02545 1/20 0.33
MAOB P27338 1/20 0.33
ALPG P10696 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlozolinate SCHEMBL21229 0.96 TSHR (0.40) ARTSHRL3MBTL1ALDH1A1TP53
Chlozolinate SCHEMBL10638292 0.96 TSHR (0.40) ARTSHRL3MBTL1ALDH1A1TP53
Chlozolinate SCHEMBL10347793 0.96 TSHR (0.40) ARTSHRL3MBTL1ALDH1A1TP53
Chlozolinate SCHEMBL10456638 0.89 TSHR (0.56) TSHRL3MBTL1ALDH1A1TP53MAPT
Chlozolinate SCHEMBL27816364 0.85 KDM4E (0.34) TSHRL3MBTL1ALDH1A1TP53MAPT
SCHEMBL11269869 0.85 ALDH1A1 (0.41) TSHRALDH1A1TP53MAPTGLA
SCHEMBL11266142 0.84 ALDH1A1 (0.44) L3MBTL1ALDH1A1MAPTLMNA
SCHEMBL11262619 0.82 L3MBTL1 (0.41) TSHRL3MBTL1ALDH1A1TP53MAPT
SCHEMBL11269738 0.82 ALDH1A1 (0.35) ARTSHRALDH1A1MAPTGLA
SCHEMBL11268442 0.82 MAPT (0.45) ARTSHRALDH1A1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431430-B1 THE USE OF MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS KOPPERS PERFORMANCE CHEMICALS INC (US) 2017-02-01 EP disclosed
EP-1799776-B1 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE INC (US) 2013-01-02 EP disclosed
EP-2431430-A1 Micronized wood preservative formulations in organic carriers Osmose, Inc. (US) 2012-03-21 EP disclosed
EP-1799776-A4 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE INC (US) 2009-05-06 EP disclosed
EP-1799776-A2 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS Osmose, Inc. (US) 2007-06-27 EP disclosed
WO-2006044218-A2 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE, INC. (US) 2006-04-27 WO disclosed