SCHEMBL11277121

SCHEMBL11277121

CCOC(=O)C1(C)OC(=O)N(c2ccccc2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
ALDH1A1 P00352 4/20 0.44
GLA P06280 1/20 0.44
GAA P10253 3/20 0.42
ELANE P08246 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
ATM Q13315 1/20 0.41
TP53 P04637 1/20 0.40
SLC22A1 O15245 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11266142 0.86 ALDH1A1 (0.44) MAPTALDH1A1GAA
SCHEMBL11269869 0.84 ALDH1A1 (0.41) MAPTALDH1A1GLAGAACTDSP1
SCHEMBL11263372 0.83 ALDH1A1 (0.39) MAPTALDH1A1GLAGAAELANE
Chlozolinate SCHEMBL10638292 0.83 TSHR (0.40) MAPTALDH1A1GLATP53OPRM1
Chlozolinate SCHEMBL10347793 0.83 TSHR (0.40) MAPTALDH1A1GLATP53OPRM1
SCHEMBL11269738 0.82 ALDH1A1 (0.35) MAPTALDH1A1GLACTDSP1OPRM1
SCHEMBL11268442 0.81 MAPT (0.45) MAPTALDH1A1GLAGAATP53
Chlozolinate SCHEMBL747833 0.80 AR (0.40) MAPTALDH1A1GLATP53OPRK1
Chlozolinate SCHEMBL10456638 0.76 TSHR (0.56) MAPTALDH1A1GLATP53OPRM1
SCHEMBL16804134 0.75 LMNA (0.44) MAPTALDH1A1GLAELANECTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4342773-A N-Aryl-1,3-oxazolidine-2,4-diones exerting a fungicidal, systemic action in the field MONTEDISON S.P.A. (IT) 1982-08-03 US claimed