Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.45 |
| ▸ | TYMS | P04818 | 3/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273089 | 0.87 | CA2 (0.52) | RAB9ANPC1CA2ERAP2 | |
| SCHEMBL11273085 | 0.87 | CA2 (0.52) | RAB9ANPC1CA2ERAP2 | |
| SCHEMBL17313759 | 0.85 | GAA (0.46) | RAB9AGAALNPEPTAS1R3TAS1R1 | |
| SCHEMBL5808668 | 0.80 | HDAC6 (0.39) | RAB9AGAA | |
| SCHEMBL5808669 | 0.80 | HDAC6 (0.39) | RAB9AGAA | |
| SCHEMBL11267792 | 0.80 | RAB9A (0.50) | RAB9AGAANPC1CA2 | |
| SCHEMBL9830744 | 0.79 | CA2 (0.54) | RAB9AGAATAS1R3TAS1R1CA2 | |
| SCHEMBL9830731 | 0.79 | CA2 (0.54) | RAB9AGAATAS1R3TAS1R1CA2 | |
| SCHEMBL11907457 | 0.79 | LNPEP (0.67) | RAB9AGAALNPEPTYMSTAS1R3 | |
| SCHEMBL17313825 | 0.78 | LNPEP (0.39) | RAB9AGAALNPEPTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337339-A | Process for preparation of folic acid derivatives | BAKER INSTRUMENTS CORP. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4326060-A | 6-FORMYLPTERIN, P-AMINOBENZOYL AMINO ACID | BAKER INSTRUMENTS CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
| US-4314988-A | Folic acid derivatives and process for preparation | BAKER INSTRUMENTS CORP. (US) | 1982-02-09 | — | — | US | disclosed |
| US-4298735-A | Folic acid derivatives | UNION CARBIDE CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |