Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.52 |
| ▸ | CA1 | P00915 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273085 | 1.00 | CA2 (0.52) | CA2CA1NPC1RAB9AERAP2 | |
| SCHEMBL1310656 | 0.88 | ACE (0.48) | CA2CA1PTPN1GPR132 | |
| SCHEMBL1310658 | 0.88 | ACE (0.48) | CA2CA1PTPN1GPR132 | |
| SCHEMBL9828763 | 0.88 | PIN1 (0.43) | CA2CA1PTPN1GPR132 | |
| SCHEMBL9828758 | 0.88 | PIN1 (0.43) | CA2CA1PTPN1GPR132 | |
| SCHEMBL11268545 | 0.87 | RAB9A (0.46) | CA2NPC1RAB9AERAP2 | |
| SCHEMBL5575842 | 0.85 | CA2 (0.43) | CA2CA1PTPN1GPR132 | |
| SCHEMBL9830744 | 0.84 | CA2 (0.54) | CA2CA1RAB9APTPN1GPR132 | |
| SCHEMBL17313791 | 0.84 | CA2 (0.40) | CA2CA1PTPN1GPR132 | |
| SCHEMBL9830731 | 0.84 | CA2 (0.54) | CA2CA1RAB9APTPN1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337339-A | Process for preparation of folic acid derivatives | BAKER INSTRUMENTS CORP. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4326060-A | 6-FORMYLPTERIN, P-AMINOBENZOYL AMINO ACID | BAKER INSTRUMENTS CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
| US-4314988-A | Folic acid derivatives and process for preparation | BAKER INSTRUMENTS CORP. (US) | 1982-02-09 | — | — | US | disclosed |
| US-4298735-A | Folic acid derivatives | UNION CARBIDE CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |