Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771322 | 0.93 | TSHR (0.35) | TSHRALDH1A1TDP1 | |
| SCHEMBL11278231 | 0.89 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL11267297 | 0.89 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL27787786 | 0.82 | — | — | |
| SCHEMBL11199403 | 0.81 | TSHR (0.48) | TSHRALDH1A1TDP1 | |
| SCHEMBL10629447 | 0.80 | THRB (0.35) | TSHR | |
| SCHEMBL1609030 | 0.80 | THRB (0.35) | TSHR | |
| SCHEMBL17644808 | 0.80 | THRB (0.35) | TSHR | |
| SCHEMBL11278778 | 0.80 | HTR1A (0.36) | TSHRALDH1A1TDP1 | |
| SCHEMBL17391488 | 0.78 | THRB (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332612-A | N-METHYL-2-PYRROLIDONE AND A HALOALKYL SILANE | GAF CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |