SCHEMBL1126868

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126804	0.73	HDAC6 (0.40)	BRD4KDM4ERAB9ASMN1; SMN2NPC1
	SCHEMBL30597848	0.68	AVPR1A (0.34)	BRD4ALDH1A1
	SCHEMBL6370173	0.67	COMT (0.44)	KDM4ERAB9ASMN1; SMN2NPC1MAPT
	SCHEMBL14541451	0.66	NPC1 (0.48)	KDM4EALDH1A1GAARAB9ASMN1; SMN2
	SCHEMBL1126871	0.63	WDR5 (0.47)	BRD4KDM4EALDH1A1RAB9ASMN1; SMN2
	SCHEMBL942428	0.62	KDM4E (0.45)	BRD4KDM4EALDH1A1GAARAB9A
	SCHEMBL1126634	0.61	NPC1 (0.59)	BRD4KDM4EALDH1A1GLAGAA
	SCHEMBL1988551	0.61	KDM4E (0.44)	BRD4KDM4EALDH1A1GAARAB9A
	Biphenyl SCHEMBL28062042	0.61	BRD4 (0.68)	BRD4ALDH1A1PARLRAB9ASMN1; SMN2
	SCHEMBL24556388	0.60	BRD4 (1.00)	BRD4KDM4EALDH1A1GLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.