SCHEMBL1126869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1990466	0.98	NPC1 (0.41)	NPC1RAB9ASMN1; SMN2MAP3K7FGFR1
	SCHEMBL1992455	0.91	NPC1 (0.43)	NPC1RAB9ASMN1; SMN2MAP3K7FGFR1
	SCHEMBL1991280	0.89	MAPT (0.42)	NPC1RAB9ASMN1; SMN2MAPTALDH1A1
	SCHEMBL1991665	0.88	HCRTR1 (0.44)	NPC1RAB9ASMN1; SMN2MAP3K7FGFR1
	SCHEMBL1992676	0.88	MAPT (0.36)	NPC1RAB9ASMN1; SMN2MAP3K7FGFR1
	SCHEMBL1993167	0.87	PANK3 (0.42)	NPC1RAB9ASMN1; SMN2MAP3K7FGFR1
	SCHEMBL1127284	0.87	MAPT (0.42)	NPC1RAB9AMAPTALDH1A1LMNA
	SCHEMBL30234731	0.87	MAPT (0.42)	NPC1RAB9AMAPTALDH1A1LMNA
	SCHEMBL1997118	0.86	ALDH1A1 (0.46)	NPC1RAB9ASMN1; SMN2MAP3K7FGFR1
	SCHEMBL1989247	0.85	MAPT (0.40)	NPC1RAB9ASMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.