Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127017 | 0.76 | RAB9A (0.64) | RAB9ASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL1126679 | 0.75 | RAB9A (1.00) | RAB9ASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL11864683 | 0.65 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL1126857 | 0.65 | KMT2A (0.64) | RAB9ASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL11732492 | 0.64 | GAA (0.55) | RAB9AMEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL1126867 | 0.64 | RAB9A (0.62) | RAB9ASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL1126474 | 0.62 | MEN1 (1.00) | RAB9ASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL1126366 | 0.61 | RAB9A (1.00) | RAB9ASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL28655154 | 0.61 | CES2 (0.39) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL28740075 | 0.61 | P4HB (0.59) | MEN1KMT2AMAPTPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |