Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203346 | 0.78 | ADRB2 (0.44) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL2588402 | 0.77 | LMNA (0.52) | TDP1LMNAAOC3 | |
| SCHEMBL2321794 | 0.77 | LMNA (0.52) | TDP1LMNAAOC3 | |
| SCHEMBL6619282 | 0.77 | LMNA (0.52) | TDP1LMNAAOC3 | |
| SCHEMBL8239806 | 0.77 | ADRB2 (0.48) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL5241824 | 0.77 | ADRB2 (0.48) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL2632879 | 0.75 | ADRB2 (0.52) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL6203092 | 0.75 | TSHR (0.48) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL10192291 | 0.75 | ADRB2 (0.52) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL14705838 | 0.75 | ADRB2 (0.52) | ADRB2TSHRMAPK1HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338453-A | Aminoalkyl-1,2,4-triazoles | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |