Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607146 | 0.89 | TDP1 (0.42) | TSHRMAPK1TDP1HIF1AADRB2 | |
| SCHEMBL6679840 | 0.81 | TSHR (0.44) | TSHRMAPK1TDP1HIF1AADRB2 | |
| SCHEMBL9398857 | 0.80 | ALDH1A1 (0.43) | TSHRMAPK1TDP1LMNASLC6A3 | |
| SCHEMBL7360258 | 0.78 | AOC3 (0.38) | TSHRMAPK1TDP1LMNASLC6A3 | |
| SCHEMBL28270153 | 0.78 | ESR1 (0.60) | TSHRTDP1HIF1ALMNASLC6A3 | |
| SCHEMBL8973238 | 0.78 | SLC6A2 (0.45) | TSHRMAPK1TDP1HIF1AADRB2 | |
| SCHEMBL8239806 | 0.77 | ADRB2 (0.48) | TSHRMAPK1TDP1HIF1AADRB2 | |
| SCHEMBL3167744 | 0.77 | TSHR (0.50) | TSHRMAPK1TDP1HIF1AADRB2 | |
| SCHEMBL212179 | 0.77 | LMNA (0.52) | TSHRTDP1LMNAAOC3 | |
| SCHEMBL5241824 | 0.77 | ADRB2 (0.48) | TSHRMAPK1TDP1HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679539-A | Compound containing bis (diphenylphosphine oxide) structure and preparation method thereof | 李萍萍 | 2021-04-20 | — | — | CN | claimed |
| CN-122059950-A | Compounds with proteasome agonistic activity, preparation method and application thereof | 浙大城市学院 | 2026-05-19 | — | — | CN | disclosed |
| CN-112679539-B | Compound containing bis-diphenyl phosphinic oxygen structure and preparation method thereof | 李萍萍 | 2024-02-13 | — | — | CN | disclosed |
| CN-112679539-A | Compound containing bis (diphenylphosphine oxide) structure and preparation method thereof | 李萍萍 | 2021-04-20 | — | — | CN | disclosed |
| EP-1525199-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS | Argenta Discovery Limited (GB) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004013130-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS | ARGENTA DISCOVERY LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |