Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | TGM1 | P22735 | 1/20 | 0.59 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 5/20 | 0.50 |
| ▸ | CHRNA9 | Q9UGM1 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126421 | 0.84 | ALDH1A1 (0.48) | F13A1TGM2TGM1TGM3ALDH1A1 | |
| SCHEMBL22495215 | 0.78 | RAB9A (0.53) | CHRNA7CHRNA10CHRNA9ALDH1A1MEN1 | |
| SCHEMBL1869426 | 0.74 | F13A1 (1.00) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL1126919 | 0.73 | HTR3E (0.52) | F13A1TGM2TGM1TGM3CHRNA7 | |
| SCHEMBL1126465 | 0.73 | HTR3E (0.63) | ALDH1A1MEN1KMT2AGAAHTR3E | |
| SCHEMBL1991472 | 0.72 | KCNH2 (0.44) | F13A1TGM2TGM1TGM3CHRNA7 | |
| SCHEMBL30235095 | 0.72 | KCNH2 (0.44) | F13A1TGM2TGM1TGM3CHRNA7 | |
| SCHEMBL31720733 | 0.72 | CHRNA7 (0.69) | CHRNA7CHRNA10CHRNA9MAPTNPC1 | |
| SCHEMBL12529092 | 0.71 | MCHR1 (0.52) | ALDH1A1MAPTKDM4E | |
| SCHEMBL31720799 | 0.71 | CHRNA7 (0.71) | CHRNA7CHRNA10CHRNA9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |