Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126418 | 0.83 | MAPT (0.44) | CHRNA7CHRNA10CHRNA9KDM4EALDH1A1 | |
| SCHEMBL1126465 | 0.79 | HTR3E (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1126920 | 0.73 | F13A1 (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL22495215 | 0.73 | RAB9A (0.53) | CHRNA7CHRNA10CHRNA9NPC1RAB9A | |
| SCHEMBL1126692 | 0.73 | SIRT6 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20339488 | 0.73 | HTR3E (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL31381324 | 0.72 | TDP1 (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6525544 | 0.71 | KCNH2 (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL240113 | 0.71 | KDM4E (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL2127461 | 0.70 | HTR3A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |