Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ACP1 | P24666 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259222 | 0.84 | NPC1 (0.49) | KMT2AALDH1A1MEN1ACP1MAPT | |
| SCHEMBL11271207 | 0.83 | MAPT (0.44) | KMT2AALDH1A1MEN1ACP1MAPT | |
| SCHEMBL11262352 | 0.83 | MAPT (0.49) | KMT2AALDH1A1MEN1MAPTNPSR1 | |
| SCHEMBL11262236 | 0.83 | MAPT (0.47) | KMT2AALDH1A1MEN1MAPTNPSR1 | |
| SCHEMBL11269297 | 0.81 | SMN1; SMN2 (0.47) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL11256671 | 0.78 | RAB9A (0.49) | KMT2AALDH1A1ACP1MAPTPOLB | |
| SCHEMBL4509401 | 0.77 | RAB9A (0.50) | KMT2AALDH1A1ACP1MAPTPOLB | |
| SCHEMBL4493348 | 0.73 | CASP2 (0.55) | KMT2AALDH1A1MEN1ACP1MAPT | |
| SCHEMBL11262749 | 0.72 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1ACP1MAPT | |
| SCHEMBL11259059 | 0.72 | MAPT (0.44) | KMT2AALDH1A1ACP1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |