Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258691 | 0.94 | NOS1 (0.44) | NOS1HMOX1ATP4AATP4BQPCT | |
| SCHEMBL11264057 | 0.91 | HMOX1 (0.46) | NOS1HMOX1ATP4AATP4BCYP19A1 | |
| SCHEMBL11269327 | 0.90 | HMOX1 (0.41) | NOS1HMOX1ATP4AATP4BQPCT | |
| SCHEMBL11266344 | 0.90 | NOS1 (0.41) | NOS1HMOX1ATP4AATP4BCYP19A1 | |
| SCHEMBL11267306 | 0.89 | NOS1 (0.46) | NOS1HMOX1ATP4AATP4BQPCT | |
| SCHEMBL11260023 | 0.89 | QPCT (0.38) | HMOX1QPCTTP53CYP19A1 | |
| SCHEMBL11265140 | 0.88 | NOS1 (0.46) | NOS1HMOX1ATP4AATP4BQPCT | |
| SCHEMBL11261780 | 0.88 | CYP19A1 (0.43) | QPCTCYP19A1 | |
| SCHEMBL11253358 | 0.87 | CYP19A1 (0.37) | HMOX1CYP19A1 | |
| SCHEMBL11271370 | 0.87 | HMOX1 (0.44) | NOS1HMOX1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |