Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715876 | 0.89 | LMNA (0.54) | NPSR1HTTLMNAMAPK1MAPT | |
| SCHEMBL11274398 | 0.88 | LMNA (0.67) | NPSR1HTTLMNAMAPK1MAPT | |
| SCHEMBL11708214 | 0.85 | NPSR1 (0.58) | NPSR1HTTLMNAMAPK1MAPT | |
| SCHEMBL30030552 | 0.84 | HTT (0.55) | NPSR1HTTLMNAMAPK1MAPT | |
| SCHEMBL11785718 | 0.81 | LMNA (0.77) | NPSR1HTTLMNAMAPK1MAPT | |
| SCHEMBL7613630 | 0.80 | NPSR1 (0.75) | NPSR1HTTLMNAMAPK1MAPT | |
| SCHEMBL11714920 | 0.80 | LMNA (0.45) | NPSR1HTTLMNAMAPK1MAPT | |
| SCHEMBL11269675 | 0.80 | NPSR1 (0.39) | NPSR1HTTLMNAMAPTALDH1A1 | |
| SCHEMBL11272068 | 0.79 | TACR1 (0.57) | KDM1ARCOR1 | |
| SCHEMBL11711531 | 0.79 | ALDH1A1 (0.57) | NPSR1HTTLMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31071-E | 6-Aza-3H-1,4-benzodiazepines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4012397-A | 2-Benzoyl-3-amino-pyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-03-15 | — | — | US | disclosed |
| US-4008223-A | SPASMOLYTIC, ANTIPHLOGISTIC, TRANQUILIZER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-02-15 | — | — | US | disclosed |
| US-3969361-A | 2-Benzoyl-3-amino-pyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-07-13 | — | — | US | disclosed |