Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | IL1B | P01584 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126629 | 0.81 | ACACB (0.37) | ACACBALDH1A1KDM4EHPGDNR3C1 | |
| SCHEMBL1127046 | 0.74 | CNR1 (0.46) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL15162449 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL1126908 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDP2RX7GAA | |
| SCHEMBL15162079 | 0.72 | ALDH1A1 (0.32) | ACACBALDH1A1KDM4EHPGDP2RX7 | |
| SCHEMBL1127699 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDP2RX7GAA | |
| SCHEMBL1126989 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HPGDP2RX7CNR1CNR2 | |
| SCHEMBL1126826 | 0.65 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL1126951 | 0.63 | CASR (0.39) | ALDH1A1KDM4EHPGDCNR1CNR2 | |
| SCHEMBL1126995 | 0.62 | GFER (0.39) | ALDH1A1KDM4EHPGDGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |