Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.38 |
| ▸ | IL1B | P01584 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127046 | 0.85 | CNR1 (0.46) | ALDH1A1KDM4EGAACNR1CNR2 | |
| SCHEMBL16588847 | 0.84 | ALDH1A1 (0.37) | ALDH1A1KDM4EGLAGAAATM | |
| SCHEMBL15162449 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ECNR1CNR2HPGD | |
| SCHEMBL1126989 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CNR1CNR2P2RX7CHRM3 | |
| SCHEMBL1127699 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAGAAP2RX7 | |
| SCHEMBL1127836 | 0.76 | P2RX7 (0.41) | ALDH1A1KDM4EGLAGAAATM | |
| SCHEMBL1126629 | 0.74 | ACACB (0.37) | ALDH1A1KDM4EGLAGAAATM | |
| SCHEMBL1126978 | 0.72 | ACACB (0.38) | ALDH1A1KDM4EGLAGAACNR1 | |
| SCHEMBL1126995 | 0.71 | GFER (0.39) | ALDH1A1KDM4EGAACNR1CNR2 | |
| SCHEMBL15162079 | 0.70 | ALDH1A1 (0.32) | ALDH1A1KDM4EGLAGAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |