Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270609 | 0.84 | HCAR1 (0.36) | CYP11B2TP53MAPTROCK2 | |
| SCHEMBL11267429 | 0.82 | MAPT (0.41) | CYP11B2LMNAMAPTALDH1A1HTT | |
| SCHEMBL11263206 | 0.82 | HCAR1 (0.42) | CYP11B2THRBTP53MAPTALDH1A1 | |
| SCHEMBL11275593 | 0.82 | SMN1; SMN2 (0.44) | CYP11B2LMNAMAPT | |
| SCHEMBL11267538 | 0.81 | CYP11B2 (0.32) | CYP11B2 | |
| SCHEMBL11278370 | 0.80 | PPARD (0.41) | CYP11B2 | |
| SCHEMBL11264984 | 0.78 | KMT2A (0.39) | CYP11B2LMNAMAPTALDH1A1HTT | |
| SCHEMBL11270269 | 0.78 | SMN1; SMN2 (0.39) | LMNAMAPTALDH1A1HTT | |
| SCHEMBL11268398 | 0.78 | ALDH1A1 (0.41) | THRBLMNAMAPTALDH1A1HTT | |
| SCHEMBL11263214 | 0.77 | HTT (0.51) | CYP11B2ALDH1A1HTTBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350701-A | 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |