Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.53 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267531 | 0.99 | MMP1 (0.56) | MMP1MMP3MMP9HDAC6SSTR5 | |
| SCHEMBL11259949 | 0.92 | HDAC6 (0.62) | MMP1MMP3MMP9HDAC6SSTR5 | |
| SCHEMBL11272285 | 0.88 | MMP1 (0.55) | MMP1MMP3MMP9HDAC6SSTR5 | |
| SCHEMBL11394282 | 0.84 | MMP1 (0.52) | MMP1MMP3MMP9HDAC6KCNH2 | |
| SCHEMBL11266702 | 0.82 | MMP1 (0.47) | MMP1MMP3MMP9HDAC6SSTR5 | |
| SCHEMBL11266077 | 0.82 | HDAC6 (0.55) | MMP1MMP3MMP9HDAC6CNR2 | |
| SCHEMBL11271882 | 0.74 | PLA2G10 (0.53) | MMP1MMP3MMP9HDAC6KCNH2 | |
| SCHEMBL4177516 | 0.73 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL4177512 | 0.73 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL4177507 | 0.73 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005647-B1 | HYDANTOIN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | Lilly Industries Limited (GB) | 1982-06-09 | — | — | EP | disclosed |
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |
| EP-0005647-A1 | Hydantoin compounds, their preparation and pharmaceutical formulations containing them | Lilly Industries Limited (GB) | 1979-11-28 | — | — | EP | disclosed |