Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FSHR | P23945 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269906 | 0.88 | MMP1 (0.54) | MMP1MMP3MMP9KCNH2HDAC6 | |
| SCHEMBL11267531 | 0.86 | MMP1 (0.56) | MMP1MMP3MMP9KCNH2HDAC6 | |
| SCHEMBL11394282 | 0.85 | MMP1 (0.52) | MMP1MMP3MMP9KCNH2HDAC6 | |
| SCHEMBL11259949 | 0.85 | HDAC6 (0.62) | MMP1MMP3MMP9KCNH2HDAC6 | |
| SCHEMBL11270800 | 0.76 | HDAC6 (0.52) | MMP1MMP3MMP9HDAC6KMT2A | |
| SCHEMBL4177516 | 0.74 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL4177512 | 0.74 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL4177507 | 0.74 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL4177514 | 0.74 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL11266077 | 0.71 | HDAC6 (0.55) | MMP1MMP3MMP9HDAC6CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005647-B1 | HYDANTOIN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | Lilly Industries Limited (GB) | 1982-06-09 | — | — | EP | disclosed |
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |
| EP-0005647-A1 | Hydantoin compounds, their preparation and pharmaceutical formulations containing them | Lilly Industries Limited (GB) | 1979-11-28 | — | — | EP | disclosed |