Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858212 | 0.73 | HTT (0.46) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL8921531 | 0.70 | ALDH1A1 (0.54) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL29750764 | 0.69 | CCNC (0.51) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17024105 | 0.69 | HNF4A (0.58) | KDM4EMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1127003 | 0.68 | GPR17 (0.54) | KDM4EALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL1330600 | 0.67 | MAPT (0.48) | KDM4EMAPTLRRK2ALDH1A1HPGD | |
| SCHEMBL8920563 | 0.67 | ALDH1A1 (0.70) | KDM4EMAPTHTTSMN1; SMN2LRRK2 | |
| SCHEMBL1585807 | 0.67 | RPA1 (0.51) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL30532583 | 0.67 | HTT (0.71) | HTTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30590664 | 0.66 | PARP1 (0.42) | KDM4EMAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | claimed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | claimed |
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | disclosed |