Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457177 | 0.82 | KMT2A (0.42) | GAAKMT2AHTTALDH1A1LMNA | |
| SCHEMBL7511680 | 0.82 | GAA (0.48) | TSHRGAAKMT2ASERPINE1HTT | |
| SCHEMBL9400310 | 0.80 | KMT2A (0.53) | TSHRGAAKMT2ASERPINE1HTT | |
| SCHEMBL9588684 | 0.80 | TSHR (0.47) | TSHRGAAKMT2ASERPINE1HTT | |
| SCHEMBL1264011 | 0.78 | TSHR (0.64) | TSHRGAAKMT2ASERPINE1HTT | |
| SCHEMBL10817965 | 0.77 | GAA (0.58) | TSHRGAAKMT2ASERPINE1HTT | |
| SCHEMBL9382414 | 0.77 | SERPINE1 (0.41) | TSHRGAAKMT2ASERPINE1HTT | |
| SCHEMBL11271389 | 0.77 | TSHR (0.39) | TSHRGAAKMT2ASERPINE1HTT | |
| SCHEMBL9765824 | 0.76 | GAA (0.43) | TSHRGAAKMT2ASERPINE1HTT | |
| SCHEMBL11459980 | 0.75 | KMT2A (0.34) | GAAKMT2AMAOBMEN1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007533-B1 | PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS STABILIZERS FOR SYNTHETIC POLYMERS | CIBA-GEIGY AG (CH) | 1982-09-22 | — | — | EP | disclosed |
| US-4234734-A | 2,2,6,6-Tetramethylpiperidine derivatives | CIBA-GEIGY CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |
| EP-0007533-A1 | Piperidine derivatives, process for their preparation and their use as stabilizers for synthetic polymers | CIBA-GEIGY AG (CH) | 1980-02-06 | — | — | EP | disclosed |